Alan H Lazarus Selected Research

RHO(D) antibody (anti-D)

1/2020	Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
6/2015	A monoclonal antibody with anti-D-like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects.
2/2005	Monoclonal antibodies that mimic the action of anti-D in the amelioration of murine ITP act by a mechanism distinct from that of IVIg.
6/2003	Mechanism of action of IVIG and anti-D in ITP.

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Alan H Lazarus Research Topics

Disease

33	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2021 - 05/2003
18	Thrombocytopenia (Thrombopenia) 01/2021 - 05/2003
10	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 12/2003
6	Hemorrhage 02/2016 - 04/2006
4	Anemia 01/2020 - 05/2003
4	Arthritis (Polyarthritis) 01/2019 - 01/2005
3	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 03/2014 - 04/2009
3	Cytopenia 03/2014 - 04/2006
2	Neonatal Alloimmune Thrombocytopenia 02/2020 - 04/2006
2	Hemolysis 01/2018 - 03/2014
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2016 - 01/2013
2	Inflammation (Inflammations) 06/2014 - 01/2013
1	Chickenpox 01/2019
1	Experimental Arthritis 01/2019
1	Disease Progression 01/2019
1	Hypoxia (Hypoxemia) 01/2018
1	Myasthenia Gravis 06/2016
1	Rheumatoid Arthritis 06/2016
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 02/2016
1	Body Weight (Weight, Body) 06/2014
1	Hemolytic Anemia 03/2014
1	Dyspnea (Shortness of Breath) 01/2012
1	Acute Lung Injury 01/2012
1	Transfusion-Related Acute Lung Injury 01/2012
1	Shock 01/2012
1	Type 2 Diabetes Mellitus (MODY) 09/2011
1	Tetanus 09/2010
1	Purpura 07/2003
1	Transfusion Reaction 05/2003

Drug/Important Bio-Agent (IBA)

30	Inosine Triphosphate (ITP)IBA 01/2021 - 05/2003
21	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021 - 05/2003
15	AntibodiesIBA 01/2021 - 05/2003
9	AntigensIBA 02/2020 - 05/2003
8	Monoclonal AntibodiesIBA 01/2020 - 05/2003
7	AutoantibodiesIBA 01/2021 - 12/2003
6	Immunoglobulin G (IgG)IBA 06/2016 - 05/2003
5	Therapeutic UsesIBA 06/2014 - 01/2005
4	RHO(D) antibody (anti-D)IBA 01/2020 - 06/2003
3	Glycoproteins (Glycoprotein)IBA 01/2021 - 04/2006
2	CollagenIBA 01/2019 - 06/2014
2	Fc Receptors (Fc Receptor)IBA 07/2010 - 02/2005
1	Pharmaceutical PreparationsIBA 01/2019
1	LuciferasesIBA 01/2018
1	Oxygen (Dioxygen)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	Erythropoietin FDA Link 01/2018
1	Hemoglobins (Hemoglobin)IBA 01/2018
1	platinum oxideIBA 01/2018
1	Heme Oxygenase-1IBA 01/2018
1	Cell Surface ReceptorsIBA 06/2016
1	IntegrinsIBA 07/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 07/2015
1	SteroidsIBA 07/2015
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 06/2014
1	Glycophorins (Glycophorin C)IBA 03/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2012
1	neonatal Fc receptorIBA 12/2011
1	Exenatide (Byetta)FDA Link 09/2011
1	Glucagon-Like Peptide 1 (GLP 1)IBA 09/2011
1	Muramidase (Lysozyme)IBA 09/2010
1	Diphtheria-Tetanus VaccineIBA 09/2010
1	VaccinesIBA 09/2010
1	gamma-Globulins (gamma-Globulin)IBA 02/2010
1	Rho(D) Immune Globulin (RhoGAM)IBA 04/2008
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2007
1	Antigen-Antibody Complex (Immune Complex)IBA 10/2006
1	IgG Receptors (Fc gamma RI)IBA 06/2006
1	Caspase 3 (Caspase-3)IBA 04/2006
1	Integrin beta3 (GPIIIa)IBA 04/2006
1	Platelet Membrane Glycoprotein IIbIBA 04/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2006
1	LipopolysaccharidesIBA 01/2006
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2006
1	Fc gamma receptor IIBIBA 02/2005
1	AlbuminsIBA 01/2005
1	Heparin (Liquaemin)FDA LinkGeneric 05/2003
1	Immunoglobulin M (IgM)IBA 05/2003

Therapy/Procedure

10	Therapeutics 01/2020 - 04/2006
1	Platelet Transfusion (Blood Platelet Transfusions) 01/2014